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Dog Lineage and divergence times – southern Asian wolves The Himalayan wolf is formed by one haplotype [43]: S2 Another study, which expressed some concerns with the earlier study, gave an estimate of , ago years and , ago years respectively. Two haplotypes w24, w25 were found to be unique to the Iberian Peninsula. One haplotype w10 was found to be common to the Iberian peninsula and the Balkans. These three populations with geographic isolation exhibited a near lack of gene flow [34]: S2 Subspecies Main article: Subspecies of Canis lupus Globally, C.

As of [update] , [8] 37 subspecies of C. Its list includes the domestic dog, dingo , eastern wolf and red wolf , but lists C. He concluded that there are only five North American subspecies: The Chambers review concluded that the subspecific status of C. Robert Wayne of the UCLA Department of Ecology and Evolutionary Biology further elaborated that the Chambers review on the taxonomy of the eastern wolf not only suffered from insufficient sampling but that it was also biased in terms of attributing the presences of the gray wolf Y chromosomes in the modern day eastern wolves to two unfounded hypotheses:

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Copyright notice This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. This article has been corrected. This article has been cited by other articles in PMC. Abstract To identify genetic changes underlying dog domestication and reconstruct their early evolutionary history, we generated high-quality genome sequences from three gray wolves, one from each of the three putative centers of dog domestication, two basal dog lineages Basenji and Dingo and a golden jackal as an outgroup.

Analysis of these sequences supports a demographic model in which dogs and wolves diverged through a dynamic process involving population bottlenecks in both lineages and post-divergence gene flow.

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Note that single ticket vending machines only accept notes of 5 and 10 yuan. The machine will dispense a round green plastic token. Touch it on the reader on entering the station and deposit it in the slot on the turnstile on leaving. The machines often reject old or worn notes. This is a stored value ticket. Touch it on the turnstile reader on entering and leaving the station.

It can also be used for purchases in convenience stores. The card can be bought from a separate stand at metro stations. These do not have any writing in English so ask directions from customer service. At Luohu station, the stand is located at Exit A. The stand displays the Shenzhen Tong cards and they cost yuan. Since Shenzhen hosted the Universiade Games, signs, exit guides and announcements at metro stations as well as trains are also in English, so it is fairly easy to get around the system without Chinese skills.

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Current status of research and treatment for non-small cell lung cancer in never-smoking females. Notably, more than half of the lung cancer cases in women occur in non-smokers. Among non-small-cell lung cancer NSCLC cases, cigarette-smokers have a greater association with squamous cell carcinoma than adenocarcinoma, which is more common in non-smokers Veliparib, a potent poly adenosine diphosphate-ribose polymerase inhibitor, augments platinum-induced DNA damage. Journal of Thoracic Oncology https: We conducted co-clinical trials in patient-derived xenograft PDX models to identify predictive biomarkers for the multikinase inhibitor dovitinib in lung squamous cell carcinoma LSCC.

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Other towns and sub-districts are expected to complete the task by year end. The community risk maps adopt signs and pictures in drawing maps to raise safety awareness among residents and prevent disasters. On the safety map of Anting, viewers can see venues with potential safety risks marked by signs in three tiers from high to low. Red round dots are the highest level alert. For example, the houses under high-voltage power lines in Zhujia Village are marked by red round dot as it has high safety hazards.

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Paleoecology Mammoth bone dwelling, Mezhirich site, Ukraine During the last Ice Age , the most recent peak is known as the Last Glacial Maximum when a vast mammoth steppe stretched from Spain eastwards across Eurasia and over the Bering land bridge into Alaska and the Yukon. The continent of Europe was much colder and drier than it is today, with polar desert in the north and the remainder steppe or tundra.

Forest and woodland were almost non-existent except for isolated pockets in the mountain ranges of southern Europe. There is no evidence of megafaunal extinctions at the height of the Last Glacial Maximum , indicating that increasing cold and glaciation were not factors. Multiple events appear to have caused the rapid replacement of one species by one within the same genus , or one population by another within the same species, across a broad area.

As some species became extinct, so too did the predators that depended on them. Paleoecology at this time Probable ancestor During the Last Glacial Maximum there were two types of wolf. The cold north of the Holarctic was spanned by a large, robust, wolf ecomorph that specialised in preying on megafauna. Another more slender form lived in the warmer south in refuges from the glaciation.

When the planet warmed and the Late Glacial Maximum came to a close, whole species of megafauna became extinct along with their predators, leaving the more gracile wolf to dominate the Holarctic.

Journal of the Science of Food and Agriculture

The fall of the Ming dynasty also caused many Chinese intellectuals to cross the divide between Confucians and Daoists. Esposito , p 64S. Esposito , p. Current scholarship sees the origins of the Longmen as more complex. This group practiced different traditions of Daoist neidan.

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